The recognition that elimination of manual interaction in the processing of immunohematology (IH) tests is well established as a substantial way to mitigate the potential for error and establish improved safety and security of test results. Using a fully automated instrument is the ideal solution to achieve the highest level of mitigation. However, fully automated instruments are not economically feasible in all circumstances, therefore, a solution that addresses as many of the critical control points in the process to meet the needs of facilities endeavoring to enhance transfusion safety is essential. A reasonable alternative that would satisfy this expectation addresses linkage of patient sample to reagents tested with reader reaction grading/ interpretation, all captured through system software. 

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