LEARNING HUB

Learning Hub

A collection of educational content about current advancements in science and technology to help promote a higher level of patient care.

A collection of educational content about current advancements in science and technology to help promote a higher level of patient care.

The Learning Hub is your resource for staying on top of the latest industry trends, news and best practices.

Learn with industry experts and thought leaders through our Ortho Science Bytes monthly podcasts, webinars, videos and additional resources — some of which provide the opportunity to earn Professional Acknowledgment for Continuing Education. You’ll gain invaluable knowledge to help your lab maximize performance and help achieve higher patient outcomes.

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Podcast

#28: Resolving Antibodies to High-Prevalence Antigens

High-prevalence antigens occur in greater than 99% of the population. Antibodies to high-prevalence antigens are rare and may be difficult to identify due to the lack of antigen-negative panel cells for these antigens. Examples of antibodies to high-prevalence antigens are: anti-k, anti-Kpb, anti-Jsb, and anti-Lub among many others There is a need to proper identify these antibodies before transfusion to differentiate clinically significant antibodies, that could cause hemolytic transfusion reactions or hemolytic disease of the fetus and newborn from those with little or no clinical relevance. Their specific identification is often difficult, labor-intensive, and time-consuming and it may be difficult to find antigen-negative compatible blood for the patient in need of a transfusion Learn in this episode clues to recognize if an antibody to a high-prevalence antigen is present and how to apply practices for their identification in the lab and additional recommendations for patient management.

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